O USO DE CÉLULAS-TRONCO NA REGENERAÇÃO PERIODONTAL
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A periodontite é definida como uma doença infecto-inflamatória crônica associada a um biofilme disbiótico, levando ao desequilíbrio da homeostase, a perda dos tecidos de suporte periodontal e podendo culminar na perda dentária. A frequente presença de defeitos ósseos periodontais leva ao crescente interesse na odontologia pela regeneração periodontal, passando pela busca constante de novos biomateriais e, mais recentemente com a introdução de terapias baseadas em células-tronco. O objetivo desta revisão de literatura é analisar o potencial terapêutico das células tronco mesenquimais na regeneração periodontal, abordando os desafios associados à sua aplicação clínica. As células-tronco mesenquimais (CTMs), particularmente aquelas derivadas do ligamento periodontal, têm demonstrado potencial significativo na regeneração de tecidos periodontais danificados. Estudos indicam que essas células possuem a capacidade de diferenciação em vários tipos celulares, incluindo osteoblastos, cementoblastos e fibroblastos, essenciais para a formação de novo tecido periodontal.
Biografia do Autor
Univeritas UNG.
Univeritas UNG.
Univeritas UNG.
Graduação em Odontologia, Mestrado e Doutorado em Clínica Odontológica - área de concentração em Dentística pela FOP UNICAMP, Proficiência em Laser pela Academy of Laser Dentistry ALD-USA. Professor Pesquisador do PPG e Graduação em Odontologia da Universidade Guarulhos - UNG. Professor do curso de Odontologia da Universidade São Judas Tadeu - USJT. Faculty Associate do departamento Dentistry/Restorative Dental Sciences, do health Science Center da University of Florida.
Univeritas UNG.
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